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Symbol
Name
ID
Timp3
tissue inhibitor of metalloproteinase 3
MGI:98754
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations

Mouse Phenotypes
cardiovascular system phenotype
abnormal artery morphology
abnormal aorta morphology
abnormal aorta wall morphology
abnormal abdominal aorta morphology
abdominal aorta aneurysm
abnormal blood vessel elastic tissue morphology
abnormal choroid vasculature morphology
abnormal retina blood vessel morphology
abnormal vascular branching morphogenesis
abnormal heart morphology
cardiac hypertrophy
abnormal heart left ventricle morphology
dilated heart left ventricle
cardiac fibrosis
dilated cardiomyopathy
decreased cardiac muscle contractility
decreased ventricle muscle contractility
abnormal cardiac muscle relaxation
decreased left ventricle developed pressure
decreased left ventricle systolic pressure
increased response of heart to induced stress
abnormal systemic arterial blood pressure
decreased systemic arterial blood pressure
abnormal blood vessel physiology
decreased vasodilation
aortitis
congestive heart failure
Availability Mouse Genotype
Timp3tm1.1(KOMP)Vlcg/Timp3tm1.1(KOMP)Vlcg
Timp3tm1Hest/Timp3tm1Hest !
Timp3tm1Osya/Timp3tm1Osya *
Timp3tm1Rkho/Timp3tm1Rkho

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory